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EPHB2 — VAV2

Pathways - manually collected, often from reviews:

• Reactome Reaction: VAV2 → EPHB2 (reaction) Marignani et al., J Cell Biol 2001, Marston et al., Nat Cell Biol 2003, Cowan et al., Neuron 2005
• Reactome Reaction: VAV2 → EPHB2 (indirect_complex) Marignani et al., J Cell Biol 2001, Cowan et al., Neuron 2005

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: VAV2 — EPHB2 (in vitro) Cowan et al., Neuron 2005

Text-mined interactions from Literome

Hebeis et al., Blood 2005 : In addition, activation of ERK ( extracellular signal regulated kinase ) required Vav1 and Vav2 in response to CD180 but was Vav1 and vav2 independent in response to LPS
Thalappilly et al., Oncogene 2010 : In this work, we show that Vav2 expression delayed epidermal growth factor receptor (EGFR) internalization and degradation, and enhanced EGFR, ERK and Akt phosphorylations