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MYLIP — RECK
Text-mined interactions from Literome
Gabriely et al., Mol Cell Biol 2008
(Disease Progression...) :
Specific inhibition of
miR-21 with antisense oligonucleotides
leads to elevated levels of
RECK and TIMP3 and therefore reduces MMP activities in vitro and in a human model of gliomas in nude mice
Han et al., CNS Neurosci Ther 2012
(Glioma...) :
Recent studies report that
miR-21 regulates cell invasion by targeting
RECK , however, the underlying transcriptional regulation of miR-21 in glioma cells remains elusive
Jung et al., J Biol Chem 2012
(Mouth Neoplasms) :
Transfection of miR-7 and
miR-21-mimics reduced the expression of
RECK through direct miRNA mediated regulation, and these miRNAs were inversely correlated with RECK in CAL 27 orthotopic xenograft tumors
Chiang et al., Biochim Biophys Acta 2013
(Breast Neoplasms...) :
Anti-miR-182 increased the MMP inhibitor
RECK protein in MDA-MB-231 cells while pre-miR-182 reduced RECK protein but not mRNA in normal mammary epithelial H184B5F5/M10 cells
Wang et al., Dig Dis Sci 2013
(Carcinoma, Squamous Cell...) :
miR-21 may be
involved in the tumorgenesis of ESCC by targeting FASL, TIMP3 and
RECK
Zhou et al., Int J Oncol 2013
(Carcinoma, Hepatocellular...) :
Overexpression of
miR-21 did not
cause degradation of PTEN or
RECK or PDCD4 mRNA but drastically inhibited its protein expression ... Consistent with these results, silencing
miR-21 increased the levels of PTEN,
RECK and PDCD4 protein, respectively
Lin et al., Br J Cancer 2013
(Lung Neoplasms...) :
We demonstrate that STAT3 upregulates
miR-92a to
repress RECK via post-transcriptional inhibition