◀ Back to TGFB3
IL2 — TGFB3
Text-mined interactions from Literome
Zhao et al., Cancer Immunol Immunother 2002
(Liver Neoplasms, Experimental) :
We have previously reported that
transforming growth factor beta ( TGF-beta ) produced by rat hepatoma cell line KDH-8 cells
suppressed the
interleukin-2 (IL-2) production of T cells and the tumoricidal activity of macrophages in KDH-8 tumor bearing rats and that the inhibition of TGF-beta production by low-dose bleomycin restored these activities significantly
Riemekasten et al., Arthritis Rheum 2003
:
Interferon-gamma (IFNgamma), interleukin-2 (IL-2), IL-4,
transforming growth factor beta , and IL-10 production
increased in response to the peptide in young mice ; only IFNgamma and
IL-2 were increased in older, diseased mice
Bry et al., Am J Obstet Gynecol 1992
(Obstetric Labor, Premature) :
Human amnion cells in monolayer culture were treated with
interleukin-1 , tumor necrosis factor, or vehicle in the
presence or absence of
transforming growth factor-beta
Brooks et al., Immunology 1992
:
Recombinant human interleukin-4 (IL-4) and
transforming growth factor-beta ( TGF-beta )
reduce recombinant
interleukin-2 (IL-2) induction of lymphokine activated killer ( LAK ) cell activity from human peripheral blood mononuclear cells ( PBMC )
Layh-Schmitt et al., Curr Opin Rheumatol 2008
(Spondylarthropathies) :
In mice,
transforming growth factor-beta and interleukin-6 are critical, whereas interleukin-23 is more important at later stages
promoting interleukin-17 production
Chakraborty et al., Clin Immunol Immunopathol 1991
:
The suppression of high-affinity
IL-2R induction on T cells did not
result from tumor necrosis factor-alpha and beta or from
transforming growth factor-beta as these cytokines were not detected in the cell-free supernatant from the MJ TIL culture
Espevik et al., Cell Immunol 1990
:
The
effect of recombinant ( r ) interleukin-1 beta ( rIL-1 beta ) and
transforming growth factor-beta ( TGF-beta ) on the production of
interleukin-2 (IL-2) and interleukin-6 (IL-6) from an antigen-specific ( LBRM-33-1A5 ) and an antigen-nonspecific ( EL-4-NOB-1 ) T-cell line was investigated
Ruegemer et al., J Immunol 1990
:
Regulatory
effects of
transforming growth factor-beta on
IL-2- and IL-4 dependent T cell-cycle progression
Ye et al., J Leukoc Biol 1995
:
Furthermore, both
transforming growth factor-beta and genistein, a tyrosine kinase inhibitor, could
suppress IL-2 and IL-12 signaling but CsA was generally inactive
Cardillo et al., Eur J Immunol 1993
(Autoimmune Diseases...) :
This suppression could not be reverted by exogenous
interleukin (IL)-2 and was not directly
dependent on the presence of IL-4, IL-10 or
transforming growth factor-beta
Marth et al., Eur J Immunol 1997
:
Regulation of
transforming growth factor-beta production by
interleukin-12
Fulton et al., J Infect Dis 1998
:
Regulation of
interleukin-12 by interleukin-10,
transforming growth factor-beta , tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra