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MAPK15 — MIF
Text-mined interactions from Literome
Mitchell et al., J Biol Chem 1999
:
Sustained
mitogen activated protein kinase ( MAPK ) and cytoplasmic phospholipase A2
activation by
macrophage migration inhibitory factor ( MIF )
Watanabe et al., J Biol Chem 2004
:
Moreover, we demonstrated that phosphorylation of PKC alpha/beta II and
MAPK in
response to
MIF was suppressed by genistein, and herbimycin A as well as by transfection of the plasmid of C-terminal Src kinase
Takahashi et al., Respir Res 2009
(Disease Models, Animal...) :
Anti-CD74 antibody inhibited
MIF induced p44/p42
MAPK phosphorylation and MIP-2 release by macrophages
Lue et al., Cell Signal 2011
:
MIF promotes
MAPK signalling through ERK1/2, while it can either activate or inhibit JNK phosphorylation, depending on the cell type and underlying stimulation context
Tarnowski et al., Mol Cancer Res 2010
(Neoplasm Invasiveness...) :
Here, we report that human rhabdomyosarcoma ( RMS ) cell lines secrete
MIF and that this chemokine ( a )
induces phosphorylation of mitogen activated protein kinase (
MAPK ) p42/44 and AKT, ( b ) stimulates RMS cell adhesion, ( c ) enhances tumor vascularization, but surprisingly ( d ) decreases recruitment of cancer associated fibroblasts ( CAF )
Chuang et al., BMC immunology 2010
(Vibrio Infections) :
We conclude that MIF regulates V. vulnificus induced IL-6 production via NF-?B activation and that p38
MAPK activation in V. vulnificus infection is not
MIF dependent