Gene interactions and pathways from curated databases and text-mining

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CEBPB — IL8

Text-mined interactions from Literome

Weber et al., J Biol Chem 2003 : Finally, overexpression of C/EBPbeta , but not p65 or Oct-1, markedly prevented TNF induced IL-8 promoter dependent transcription ... Taken together, these data indicate that the expression of IL-8 is inhibited at the transcriptional level in TNF-tolerant cells and C/EBPbeta is involved under these conditions in mediating the negative-regulatory effects, a mechanism that may play a role in inflammatory processes such as sepsis
Zhu et al., J Biol Chem 2003 : Transcriptional regulation of interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid independent activation of NF-kappaB