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IRF6 — IRG1

Text-mined interactions from Literome

Sugiyama et al., Microbiol Immunol 2004 : 2-AP also reduced the expression of IFN-beta and IFN-inducible genes, such as IFN-gamma-inducible protein ( IP ) -10 and immune-responsive gene (IRG)-1 , and the inducible type of NO synthase (iNOS) mRNA in response to LPS
Lee et al., Immunogenetics 1995 : The role of the protein kinase A pathway in regulating the induction of IRG1 by LPS is questionable, because although forskolin inhibited its induction, neither dibutyrl-cAMP nor 8- ( 4-chlorophenylthio ) -cAMP had much effect on its expression ... Inhibiting tyrosine phosphorylation abrogated the induction of IRG1 by LPS ... Hence, the induction of IRG1 by LPS is mediated by tyrosine kinase and protein kinase C pathway