Hammond et al., Climacteric 2008
:
Estetrol does not stimulate ERalpha mediated increases in SHBG production by HepG2 or Hep89 cells, in contrast to ethinylestradiol, estradiol and estriol
Barkhem et al., J Steroid Biochem Mol Biol 1997
(Carcinoma, Hepatocellular...) :
Both tamoxifen and raloxifene had an additive effect to estrogen receptor dependent SHBG gene expression in the HepER3 cells in the presence of saturating concentrations of moxestrol