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IL12A — KLRC1

Text-mined interactions from Literome

Seo et al., Clin Exp Immunol 2000 (Epstein-Barr Virus Infections...) : Freshly isolated leukaemic NK cells transcribed mRNA for CD94 associated molecule NKG2C at an abnormally high level, and upon stimulation with IL-2 and/or IL-12 they expressed NKG2A as well
Derre et al., J Immunol 2002 (Melanoma) : Expression of CD94/NKG2-A on human T lymphocytes is induced by IL-12 : implications for adoptive immunotherapy ... Expression of CD94/NKG2-A on human T lymphocytes is induced by IL-12 : implications for adoptive immunotherapy ... We show that IL-12 induces the expression of NKG2-A and/or CD94 by CD8 ( + ) T cells in culture, and that this induction was mediated neither by IFN-gamma nor by IL-15 ... We also show, using the redirected killing assay, that IL-12 induced expression of both CD94 and NKG2-A led to the acquisition by T cells of a functional inhibitory receptor
Zhang et al., Hum Immunol 2008 : In the present study, we explored the effect of IL-12 upregulation on the NK receptor NKG2D and on the promotion of NK cell function