Gene interactions and pathways from curated databases and text-mining

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CYP2E1 — PTGS2

Text-mined interactions from Literome

Nieto et al., J Biol Chem 2000 : Incubation with NS-398, a COX-2 inhibitor, blocked the effect of AA, but not of ethanol, on COL1A2 expression suggesting that CYP2E1 activates COX-2 expression, and the oxidation of AA by COX-2 is responsible for the increase in COL1A2
Bertrand-Thiebault et al., Clin Exp Pharmacol Physiol 2004 (Varicose Veins) : In non-varicose veins, CYP1B1, CYP2C, CYP2E1 and CYP4A11 were detected , whereas CYP2J2, CYP3A5, COX-1 and COX-2 were detected almost exclusively in varicose veins