Gene interactions and pathways from curated databases and text-mining

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ACPP — EGF

Text-mined interactions from Literome

Beck et al., Proc Natl Acad Sci U S A 2007 : Wild-type Egf1.0 inhibited PAP-3 from Manduca sexta, whereas Egf1.0 ( R51A ), whose reactive-site arginine was replaced with an alanine, had no PAP-3 inhibitory activity
Stefanović et al., Kidney Blood Press Res 1998 : EGF stimulated 5'-nucleotidase and aminopeptidase N activities in intact human mesangial cells in a time- ( 24-72 h ) and dose dependent ( 0.1-50 ng ml(-1) ) manner ... In contrast, genistein ( 10 mg x ml(-1) ), an inhibitor of tyrosine kinase, prevented EGF dependent stimulation of aminopeptidase N and 5'-nucleotidase , suggesting that protein phosphorylation was involved in the signaling mechanism