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EGFR — GRAP2
Text-mined interactions from Literome
Kolb et al., Int J Cancer 2007
(Pancreatic Neoplasms) :
HRGs induced phosphorylation of different
ErbB receptors as well as
activation of MAPK,
p38MAPK , JNK and PI3K in a cell- and ligand-specific manner
Muscella et al., Biochem Pharmacol 2009
:
Inhibition or down regulation of
EGFR reduced ( 1 ) the phosphorylation of
MAPK/p38 , ( 2 ) the cisplatin provoked activation of PKC-epsilon, and ( 3 ) the activation of caspase-7 and PARP cleavage and the overall cells sensitivity to cisplatin
Hwang et al., Mol Nutr Food Res 2011
(Fibrosarcoma...) :
Capsaicin inhibited the EGF induced invasion and migration of human fibrosarcoma cells via
EGFR dependent FAK/Akt, PKC/Raf/ERK,
p38 mitogen activated protein kinase ( MAPK ), and AP-1 signaling, leading to the down-regulation of MMP-9 expression