Gene interactions and pathways from curated databases and text-mining

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BMP2 — MEF2C

Text-mined interactions from Literome

Wu et al., Stem Cells Dev 2010 : Further, luciferase reporter assays and chromatin immunoprecipitation experiments showed that BMP-2 expression in ES cells is regulated directly by the transcription factor myocyte enhancer factor 2C , a well-known substrate of p38 MAPK
Klaus et al., Proc Natl Acad Sci U S A 2012 (Wnt Signaling Pathway) : Using FACS enrichment of cardiac progenitors in RBPJ and RBPJ/Axin2 mutants, embryo cultures in the presence of the Bmp inhibitor Noggin, and by crossing a Bmp4 mutation into the RBPJ/Axin2 mutant background, we show that Wnt and Bmp4 signaling activate specific and nonoverlapping cardiac-specific genes in the cardiac progenitors : Nkx2-5, Isl1 and Baf60c are controlled by Wnt/ß-catenin, and Gata4, SRF, and Mef2c are controlled by Bmp signaling