Gene interactions and pathways from curated databases and text-mining

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CD59 — IFNG

Text-mined interactions from Literome

Schmitt et al., Eur J Cancer 1999 (Gastrointestinal Neoplasms) : The effects of IFN-gamma on mRNA and protein expression levels of CD46, CD55 and CD59 were evaluated by Northern blot hybridisation, RT-PCR, flow cytometry and immunostaining
Mason et al., Blood 1999 : Tumor necrosis factor alpha (TNFalpha) and interferon gamma (IFNgamma) each increased DAF expression but not CD59 or MCP expression, and a combination of these cytokines was more potent than either alone
Spiller et al., Clin Exp Immunol 2000 (Acute-Phase Reaction...) : Interferon-gamma reduced expression of CD59 and strongly antagonized the up-regulatory effects on CD59 mediated by the other cytokines
Grubbs et al., Xenotransplantation 2003 : We found that induction of CD59 up-regulation required specific binding of the lectin to terminal alphaGal and was not induced either by soluble factors that may be released from EC by stimulation with the lectin or by TNF-alpha, IFN-gamma , or IL-1alpha
Halme et al., Mol Immunol 2009 (Hepatitis) : The expression of CD59 could be augmented by IL-1 beta, IL-6 and TNF-alpha but was suppressed by IFN-gamma