Gene interactions and pathways from curated databases and text-mining

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CNP — IL2

Text-mined interactions from Literome

Wen et al., Marine drugs 2011 : CNP also significantly promoted the production of Th1 ( IL-2 and IFN-? ) and Th2 ( IL-10 ) cytokines and up-regulated the mRNA expression of IL-2 , IFN-? and IL-10 cytokines in splenocytes from the immunized mice compared with OVA and CS groups
Suga et al., Endocrinology 1993 : While interleukin (IL)-2 had no significant effect on CNP secretion, IL-1 alpha, IL-1 beta and tumor necrosis factor (TNF)-alpha stimulated CNP secretion in a time- and dose dependent manner