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PTGES — PTGS2

Text-mined interactions from Literome

Yucel-Lindberg et al., Inflammation 2004 : The COX-2 specific inhibitor, celecoxib, in contrast to the nonspecific COX inhibitor, indomethacin, markedly reduced mPGES-1 expression induced by IL-1beta
Gómez-Hernández et al., Atherosclerosis 2006 (Carotid Artery Diseases) : We have studied COX-2 , mPGES-1 and PGE2 receptors ( EPs ) expression in peripheral blood mononuclear cells ( PBMC ) and atherosclerotic plaques of 29 patients with carotid stenosis as well as the effect of different nuclear factor-kappaB (NF-kappaB) inhibitors on COX-2, mPGES-1 and EPs expression in cultured monocytic cells ( THP-1 )
Nagataki et al., Cell Biochem Funct 2008 : The PAR2 triggered up-regulation of mPGES-1 was suppressed by inhibitors of COX-1, cytosolic phospholipase A ( 2 ) ( cPLA(2) ) and MEK, but not COX-2
Kunze et al., Prostaglandins Other Lipid Mediat 2010 (Inflammation) : IL1beta, TNF-alpha and LPS enhanced the expression of COX-2 and mPGES1 whereas phorbol ester enhanced COX-2 expression only
Ikeda-Matsuo et al., Br J Pharmacol 2010 (Brain Ischemia...) : This study examines the hypothesis that mPGES-1 activity is required for COX-2 to cause neuronal damage in ischaemic injury