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JUN — MSK32
Text-mined interactions from Literome
Gesser et al., Inflamm Res 2011
(Psoriasis) :
Dimethylfumarate inhibits MIF induced proliferation of keratinocytes by inhibiting
MSK1 and RSK1 activation and by
inducing nuclear
p-c-Jun ( S63 ) and p-p53 ( S15 ) expression ... Our results indicate that the specific inhibitory effects of DMF on RSK1 and
MSK1 activation together with the
induction of
p-c-Jun ( S63 ) and p-p53 ( S15 ) lead to the inhibition of keratinocyte proliferation, partly explaining the anti-psoriatic effect of DMF
Li et al., BMC cancer 2013
(Cell Transformation, Viral...) :
Using MSK1 inhibitor H89 or siRNA-MSK1, the regulatory
role of
MSK1 on histone H3 phosphorylation and
AP-1 activation were analyzed