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NFKB1 — PLAT

Text-mined interactions from Literome

Gingras et al., Biochem Biophys Res Commun 2004 : These results suggest that Neovastat induces tPA gene transcription through activation of the JNK and NFkappaB signaling pathways, leading to an increase of tPA secretion by endothelial cells
Zhang et al., Am J Pathol 2007 (Brain Ischemia...) : In conclusion, our results demonstrate that after MCAO the interaction between tPA and LRP results in NF-kappaB activation in astrocytes and induction of inducible nitric-oxide synthase expression in the ischemic tissue, suggesting a cytokine-like plasminogen independent role for tPA during cerebral ischemia