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NFKB1 — PTX3

Text-mined interactions from Literome

Tonon et al., Eur J Immunol 2002 : Secondly, studies on DC generated in vitro by culturing monocytes with IL-4 and GM-CSF showed that PTX directly stimulates MHC class II and costimulatory molecules up-regulation, cytokine synthesis and NF-kappa B activation
Iordanskiy et al., Virology 2002 : Instead, PTX-B activity is mediated through suppression of the cellular transcription factor, NF-kappaB
Ferlito et al., J Endotoxin Res 2002 : Neither PTx nor PP2 inhibited LPS induced activation of interleukin receptor activated kinase ( IRAK ) or inhibited translocation of NF-kappaB
Rizzi et al., Eur J Immunol 2004 (HIV Infections) : Here we demonstrate that PTX-B inhibits Tat dependent NF-kappaB activation and HIV-1 LTR-transactivation in non-permissive epithelial HL3T1 cells in a phosphatidylinositol 3'-kinase dependent way
Ji et al., Ann Clin Lab Sci 2004 (Disease Models, Animal...) : At all dosages, PTX reduced the activation of NF-kappaB and the production of TNF-alpha and IL-6, but enhanced the release of IL-10
Ji et al., Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 2006 (Disease Models, Animal...) : To investigate whether pentoxifylline ( PTX ) could influence the increased cytokine gene expression in the retina flowing transient ischemia, and if so, whether it acts through the modulation of nuclear factor kappa B (NF-kappaB) activation
Kim et al., Cancer Lett 2008 : As examined by the DNA binding of NF-kappaB activation, we found that PTX-2 suppressed constitutive NF-kappaB activation and determined by p65 and p50 nuclear translocation, and IkappaBalpha degradation through dephosphorylation of Akt
Arita et al., World J Gastroenterol 2008 (Adenocarcinoma...) : The translocation of NF-kappaB was similarly attenuated by PTX and U73122, but phorbol ester, an activator of protein kinase C, alone did not translocate NF-kappaB
Ganta et al., Mol Pharm 2009 : In this study, we have examined augmentation of therapeutic efficacy upon coadministration of paclitaxel ( PTX ) and curcumin ( CUR ), an inhibitor of nuclear factor kappa B (NFkappaB) as well as a potent down-regulator of ABC transporters, in wild-type SKOV3 and drug resistant SKOV3 ( TR ) human ovarian adenocarcinoma cells
Nishida et al., J Biol Chem 2010 : PTX increased the expression of IL-1beta and AT1R through NF-kappaB , and a small GTP binding protein, Rac, mediated PTX induced NF-kappaB activation through NADPH oxidase dependent production of reactive oxygen species
Biswas et al., Proc Natl Acad Sci U S A 1993 : A cooperative action of PTX ( NF-kappa B inhibitor ) and Ro 24-7429 ( Tat inhibitor ) on HIV-1 LTR regulated gene expression is suggested
Navarro et al., AIDS 1996 : Moreover, PTX reduced TNF-alpha, IFN-gamma and IL-10 production and NF-kappa B activation
Biswas et al., Mol Med 1994 : PTX inhibited PKC- or PKA catalyzed activation of NF-kappa B in cytoplasmic extracts from unstimulated Jurkat or 293-27-2 cells, but not interaction of preactivated NF-kappa B with its motifs
Pryhuber et al., Am J Physiol 1998 : The effects of PDTC and PTX on NF-kappa B and the surfactant proteins suggest that NF-kappa B activation does not mediate TPA or TNF-alpha inhibition of SP-A and SP-B mRNA accumulation