Gene interactions and pathways from curated databases and text-mining

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NPM1 — RELA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lin et al., Cell Signal 2006 : The results demonstrate a novel mechanism for transcriptional regulation of E2F1 and identify the functional role of nucleophosmin/B23 in modulating the binding of NF-kappaB , E2F1 and pRB to activate E2F1 promoter
Csiszar et al., J Appl Physiol 2008 (Cardiovascular Diseases...) : We also discuss the possibility that nucleophosmin ( NPM or nuclear phosphoprotein B23 ), a known modulator of the cellular oxidative stress response, may also regulate NF-kappaB activity in endothelial cells
Khandelwal et al., Cell Death Differ 2011 : We show by multiple approaches that nucleolar translocation of RelA is causally involved in the relocalization of NPM from the nucleolus to the cytoplasm and that RelA induced cytoplasmic NPM mediates apoptosis by facilitating the mitochondrial accumulation of BAX