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CSF1 — IL6

Text-mined interactions from Literome

Gruber et al., J Immunol 1992 : LPS and IL-1 beta, but not IL-6 or TNF-alpha, dramatically augmented the ability of anti-CD45, anti-CD44, and anti-LFA-3 antibodies to induce M-CSF secretion but failed to stimulate M-CSF secretion in the absence of antibody
Frei et al., J Neuroimmunol 1992 : Here we report that in addition to GM-CSF, murine astrocytes also produce macrophage (M)-CSF upon stimulation with tumor necrosis factor alpha, interleukin-1 and lipopolysaccharides
Dehghani et al., Exp Neurol 2004 (Gliosis) : In contrast, clodronate significantly reduced the microglial IL-6-release induced by M-CSF , indicating different intracellular pathways
Takamiya et al., J Neurotrauma 2007 (Brain Injuries...) : Among cytokines analyzed in the present study, IL-1beta, IL-5, IL-6 , IL-12 p40, G-CSF, IFN-gamma, KC, LIF, MIP2, and PDGF BB increased during the early phase of cerebral wound healing, and M-CSF increased during the middle phase, while IL-15, IL-18, and MIG increased during the late phase
Ito et al., Arthritis Res Ther 2011 (Arthritis, Rheumatoid...) : Exogenous addition of IL-17 dramatically enhanced the spontaneous production of IL-6 and prostaglandin E2 ( PGE2 ) by the ST-derived inflammatory cells, while it had no effect on the production of tumor necrosis factor (TNF)-a and macrophage colony stimulating factor ( M-CSF )
Evans et al., J Leukoc Biol 1995 (Inflammation) : Evidence that the mononuclear phagocytes, as opposed to B or T cells, were the targets of CSF-1 was obtained in two ways : ( 1 ) PCs from B6 scid/scid and NOD scid/scid mice consisting of 78-86 % MAC-1+, F4/80+ cells and few B or T cells, as shown by flow cytometry analysis, released 5- to 10-fold more IL-6 in response to CSF-1 stimulation than B6 PCs, which contained approximately 30 % double positive cells, and ( 2 ) pretreatment of B6 PCs with antibodies to the CSF-1 receptor blocked the CSF-1 induced secretion of IL-6
Hamilton et al., J Leukoc Biol 1993 : We demonstrate with elutriation purified human monocytes that, in contrast to lipopolysaccharide, recombinant human CSF-1 does not induce secretion of prostaglandin E2, interleukin-6 (IL-6), IL-1 beta, or tumor necrosis factor alpha, as measured by immunoassay ; however, increased urokinase-type plasminogen activator ( u-PA ) activity in cell lysates and mRNA was observed ... We demonstrate with elutriation purified human monocytes that, in contrast to lipopolysaccharide, recombinant human CSF-1 does not induce secretion of prostaglandin E2, interleukin-6 (IL-6) , IL-1 beta, or tumor necrosis factor alpha, as measured by immunoassay ; however, increased urokinase-type plasminogen activator ( u-PA ) activity in cell lysates and mRNA was observed
Dupuis et al., Biochim Biophys Acta 1996 : While GM-CSF ( 10 ng/ml ) and interleukin-1 ( 10 U/ml ) stimulated M-CSF production from monocyte derived macrophages, PAF did not
Suzumura et al., Brain Res 1996 : Neither IL-3 nor macrophage-CSF (M-CSF) induced IL-6 production in microglia
Held et al., J Interferon Cytokine Res 1996 : These may caused by differences in the M-CSF induced production of TNF-alpha and IL-6
Lemaire et al., J Immunol 1996 : In contrast, IL-6 mRNA expression was increased by GM-CSF but not M-CSF
Kamdar et al., Exp Cell Res 1997 : It has been recently shown that CSF-1 enhanced the constitutive expression of the Il6 gene in resident mouse peritoneal macrophages ( PM phi ) but little is known about the pathways involved ... In this report, we show that both constitutive and CSF-1 induced IL-6 release were enhanced and prolonged in the presence of the PKC inhibitors, staurosporine ( SP ) and its derivative, GF-109203X ... These data indicate that CSF-1 does not induce Il6 gene expression by amplifying the constitutive pathway in all mononuclear phagocyte subpopulations ... It is also apparent that multiple PKs, excluding PKC, may be involved in repressing constitutive and CSF-1 induced Il6 gene expression
Asakura et al., Immunopharmacology 1997 : However, M-CSF-injection had lesser effects on LPS induced IL-6 production from liver, alveolar and peritoneal macrophages
Hanamura et al., Immunopharmacology 1997 (Escherichia coli Infections...) : M-CSF at 250 micrograms/kg/day for 3 days significantly augmented serum IL-6 level induced by a subsequent injection of 25 micrograms/kg of LPS
Menetrier-Caux et al., Blood 1998 (Carcinoma, Renal Cell) : Interleukin-6 (IL-6) and macrophage colony stimulating factor ( M-CSF ) were found to be responsible for this phenomenon : antibodies against IL-6 and M-CSF abrogated the inhibitory effects of RCC CM ; and recombinant IL-6 and/or M-CSF inhibited the differentiation of DC similarly to RCC CM
Evans et al., J Leukoc Biol 1998 : CSF-1 regulation of Il6 gene expression by murine macrophages : a pivotal role for GM-CSF ... PMphi from C57BL/6J-Csfgm ( null ) mice were shown to release minimal IL-6 in response to CSF-1 and to express a much reduced response to the highly stimulatory combination of CSF-1 and lipopolysaccharide (LPS)