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MICE — NOS2
Text-mined interactions from Literome
Brunet et al., J Immunol 1999
(Hepatomegaly...) :
Mice treated with aminoguanidine, a selective
inhibitor of
iNOS , exhibited cachexia and exacerbated liver pathology, suggesting that NO limits hepatocyte damage when the liver is first exposed to eggs
Kelley et al., J Clin Invest 2000
(Cystic Fibrosis) :
Mice lacking IRF-1 expression have
diminished epithelial
NOS2 expression, as well as reduced NO-dependent chloride transport across the nasal epithelia
Summers et al., J Am Soc Nephrol 2009
(Disease Models, Animal...) :
Mice injected with Th1 cells developed progressive albuminuria over 21 d, histologic injury including 5.5 +/- 0.9 % crescent formation/segmental necrosis, elevated urinary nitrate, and
increased renal
NOS2 , CCL2, and CCL5 mRNA