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EGF — IVL

Text-mined interactions from Literome

Rosdy et al., In Vitro Cell Dev Biol 1986 (Carcinoma, Squamous Cell) : In other respects, EGF , which inhibits the proliferation of A431 cells, enhances involucrin accumulation in these cells, although in normal human keratinocytes it stimulates growth and reduces involucrin synthesis
Rosdy et al., In Vitro Cell Dev Biol 1988 : Opposite effects of EGF on involucrin accumulation of A431 keratinocytes and a variant which is not growth arrested by EGF ... We reported earlier that EGF induces involucrin accumulation in A431 cells and proposed that the arrest of proliferation triggers differentiation as shown by the induction of this cornified envelope precursor protein ... These opposite effects of EGF on the expression of terminal differentiation marker involucrin in A431 and A431 clone 15 keratinocytes were observed in defined medium as well as in presence of fetal calf serum