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IGF1 — ZNF143

Text-mined interactions from Literome

Paek et al., Exp Mol Med 2010 (Colonic Neoplasms) : IGF-1 induces expression of zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species ... Taken together, these data suggest that IGF-1 induces ZNF143 expression in cancer cells via PI3-kinase and reactive oxygen species generation during receptor internalization
Paek et al., Mol Cells 2011 (Colonic Neoplasms) : GAIP interacting protein, C-terminus is involved in the induction of zinc-finger protein 143 in response to insulin-like growth factor-1 in colon cancer cells ... The knockdown of GIPC in colon cancer cells reduced ZNF143 expression in response to IGF-1 ... IGF-1 signaling through its receptor, leading to the phosphorylation and activation of the PI3-kinase-Akt pathway and mitogenactivated protein kinases ( MAPKs ) was unaffected by the knockdown of GIPC, indicating the independence of the GIPC linked pathway from PI3-kinase- and MAPK linked signaling in IGF-1 induced ZNF143 expression