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IFI44 — SYK

Text-mined interactions from Literome

Andreae et al., Blood 2003 : Engagement of class II molecules by both its natural ligand LAG-3 and class II mAb induces rapid protein phosphorylation of phospholipase Cgamma2 ( PLCgamma2 ) and p72syk as well as activation of phosphatidyl inositol 3-kinase/Akt, p42/44 extracellular signal regulated protein kinase, and p38 mitogen activated protein kinase pathways
Takada et al., J Immunol 2004 : Overall, our results demonstrate that Syk activation plays an essential role in TNF induced activation of JNK, p38 MAPK, p44/p42 MAPK, NF-kappaB, and apoptosis