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IRF6 — TGFB1

Text-mined interactions from Literome

Hu et al., J Leukoc Biol 1999 : Anti-inflammatory cytokines, IL-10, and transforming growth factor ( TGF ) -beta sequentially inhibited LPS- and cytokine induced microglial cell NF-kappaB activation, RANTES mRNA expression, and protein release
Gutiérrez-Ruiz et al., Toxicology 1999 : With the same time of exposure, LPS reduced slightly TGF-beta1 expression, and decreased its secretion
Schrader et al., J Exp Med 1999 : Splenic B cells from mice deficient in Msh2, Mlh1, Pms2, or Mlh1 and Pms2 were stimulated in culture with lipopolysaccharide (LPS) to induce immunoglobulin ( Ig ) G2b and IgG3, LPS and interleukin (IL)-4 to induce IgG1, or LPS, anti-delta-dextran, IL-4, IL-5, and transforming growth factor (TGF)-beta1 to induce IgA
Imai et al., FEBS Lett 1999 : TGF-beta1 inhibited LPS-stimulation of phosphorylated JNK1 and JNK2 and consequently of JNK activity in the cells
Ledeboer et al., Glia 2000 : LPS induced levels of IL-1beta were suppressed by IL-10, but not by IL-4 and TGF-beta1/beta2
Imai et al., Infect Immun 2000 : TGF-beta1 markedly inhibited LPS stimulation of CD14 mRNA and protein levels in mouse macrophages
Lieb et al., Neurochem Int 2003 (Multiple Sclerosis) : Among the substances tested, the glucocorticoids prednisone, hydrocortisone, dexamethasone and progesterone as well as transforming growth factor-beta ( TGF-beta ) dose-dependently inhibited LPS induced nitric oxide synthase (iNOS) and NO synthesis
Min et al., Mol Cells 2003 : LPS , particularly in the presence of IFN-gamma, induced P388D1 cells to secrete active TGF-beta1
Shin et al., J Ethnopharmacol 2004 (Fatigue Syndrome, Chronic) : KBT ( 1 mg/ml ) significantly inhibited LPS induced tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 production in PBMC of CFS patients
Antonicelli et al., Am J Physiol Lung Cell Mol Physiol 2004 (Pneumonia) : However, only LPS induced IL-8 and TGF-beta1 expressions were inhibited by NAL
Ming et al., Zhonghua Shao Shang Za Zhi 2004 : Apoptosis and TGFbeta(1) secretion could be induced by LPS in dose of 0.1 to 100 micro g/ml when compared with that without LPS challenge ( P < 0.05 - 0.01 )
Rae et al., Biochem Biophys Res Commun 2006 (Atrophy) : LPS induced TGFbeta1 release and SMAD4 nuclear translocation 96 h after treatment
El Gazzar et al., Inflamm Res 2007 (Inflammation) : LPS induced HMGB1 release at 8 h and reached a peak at 48 h. Significant ( p < 0.05 ) production of TNFalpha, IL-1beta, IL-10, and TGF-beta1 was seen after 8 h
Choi et al., J Surg Res 2007 (Fibrosis) : PT inhibited LPS induced TGF-beta1 mRNA expression and protein secretion in GBEC in both culture systems
Widing et al., Transfusion 2007 : The lipopolysaccharide (LPS) induced production of tumor necrosis factor (TNF)-alpha and transforming growth factor (TGF)-beta1 from CB monocytes was analyzed after incubation with addition of weekly sampled supernatants from the CB RBC units ... During storage in both media, the number of white blood cells ( WBCs ) decreased, and the LPS induced production of TNF-alpha and TGF-beta1 decreased and increased, respectively ... There were no significant changes in the LPS induced production of TNF-alpha and TGF-beta1 in the leukoreduced CB RBC units ... The changes in LPS induced TNF-alpha and TGF-beta1 production over time were probably caused by substances released from apoptotic and/or necrotic WBCs
D'Souza El-Guindy et al., Alcohol 2007 (Alcoholic Intoxication...) : EtOH suppressed upregulation of TGF-beta1 mRNA expression by LPS and blocked completely LPS induced TGF-beta1 secretion
Hamby et al., Neurochem Int 2008 (Encephalitis...) : A recent study examining the regulation of astrocytic NOS-2 expression demonstrated that transforming growth factor-beta1 ( TGF beta 1 ) potentiated LPS plus IFN gamma induced NOS-2 expression via expansion of the pool of astrocytes that express NOS-2
Hamby et al., Prostaglandins Other Lipid Mediat 2008 : We found that TGF-beta1 augmented LPS plus IFNgamma induced COX-2 mRNA and protein expression, by nearly tripling the number of astrocytes that express COX-2
Mayer et al., Marine drugs 2007 : Furthermore, both LPS and domoic acid did not significantly affect TGF-beta1 gene expression and protein release
Chiu et al., Clin Nutr 2010 : Lipopolysaccharide (LPS) induced proinflammatory cytokines ( IL-1beta, IL-6, IL-8, TNF-alpha ) and anti-inflammatory TGF-beta1 were determined
Pei et al., Int Immunopharmacol 2010 (Prostatic Neoplasms) : Sodium selenite inhibits the expression of VEGF, TGFbeta(1) and IL-6 induced by LPS in human PC3 cells via TLR4-NF-(K)B signaling blockage ... Using real-time quantitative PCR and ELISA analysis, we found that pretreatment with selenium ( 0.5-5uM ) inhibited the LPS induced expression of TGFbeta(1) and VEGF and production of these cytokines and IL-6 by PC3 cells, but did not alter the expression of TLR4 mRNA
Hamby et al., Glia 2010 : Overall, this data suggests that ALK5 signaling and Smad3 nuclear accumulation is required for optimal enhancement of LPS plus IFNgamma induced NO production in astrocytes by TGF-beta1
Hausmann et al., Infect Immun 1994 : This study was designed to determine the effects of recombinant transforming growth factor beta 1 ( rTGF-beta 1 ) on macrophage activation by LPS
Gardiner et al., Br J Pharmacol 1995 : 4. In the presence of LPS , haemodynamic responses to L-NMMA were suppressed, and TGF-beta 1 generally did not affect this suppression
Pender et al., Eur Cytokine Netw 1996 (Shock, Septic) : These data suggest that TGF-beta 1 inhibits LPS stimulated MO 6-keto-PGF-1 alpha production by acting at, or distally to, phospholipase A2, possibly at the level of cyclooxygenase in the arachidonic acid cascade
Kang et al., Shock 1996 : The effects of TGF-beta 1 on LPS induction of the adhesion molecules varied with LPS concentration and treatment time, mode, and duration ... TGF-beta 1 effects on LPS induction of the adhesion molecules were more prominent at lower LPS levels ( .001, .01 microgram/mL )
Martín-Sanz et al., Br J Pharmacol 1998 : Also, transforming growth factor-beta inhibited the LPS- and pro-inflammatory cytokines dependent expression of COX-2