Guarneri et al., Breast Cancer Res Treat 2008
(Breast Neoplasms) :
Adding gefitinib to chemotherapy did not result in different effects on the EGFR dependent pathway, proliferation, apoptosis and VEGFR2 expression as compared to placebo, while enhancing skin and mucosal toxicity
Ichihara et al., Cancer Res 2009
(Adenocarcinoma...) :
Compared with PC-9 cells, PC-9/VanR cells showed emergence of an EGFR T790M mutation, moderately elevated MET amplification, and similar VEGFR-2 inhibition by vandetanib