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EGR2 — IL2

Pathways - manually collected, often from reviews:

• NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes: EGR2 (EGR2) → IL2 (IL2) (transcription, inhibits) Safford et al., Nat Immunol 2005
  Evidence: mutant phenotype

Text-mined interactions from Literome

Xiao et al., Eur J Immunol 1999 : FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3
Miao et al., J Immunol 2013 (Inflammation) : We have now discovered that Egr-2 , which is induced by TGF-ß and IL-6, negatively regulates the expression of IL-17, but not IL-2 or IFN-?, in effector T cells