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P2RY1 — PRKAR2B

Text-mined interactions from Literome

Guerra et al., Pflugers Arch 2004 : These data suggest that the X laevis P2Y1 receptor in A6 cells can increase both cAMP/PKA and Ca2+/PKC intracellular levels and that the PKC pathway is involved in CFTR activation via potentiation of the PKA pathway
Akimova et al., J Physiol 2005 : The rank order of potency ( 2MeSATP > ATP > ADP > > UTP ) indicates that P 2Y1 rather than P 2Y2 receptors contribute to PKA and I ( SC ) activation ... Viewed collectively, these data show that Cl- secretion in C7-MDCK monolayers treated with basolateral ATP is triggered by P 2Y1 receptors and is mediated by subsequent [ Ca2+ ] i-independent activation of PLA2 and PKA