We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to GRAP2

GRAP2 — MEFV

Text-mined interactions from Literome

Burton et al., Brain Res Mol Brain Res 2002 (Alzheimer Disease...) : A model of anti-apoptotic APP signaling is proposed where APP mediates p38 MAPK dependent phosphorylation and activation of MEF2
Lee et al., Mol Cell Biol 2003 (MAP Kinase Signaling System) : We found TNF-alpha induced p38 MAP kinase activation and interleukin-6 (IL-6) production impaired in rip1 ( -/- ) murine embryonic fibroblasts (MEF) but unaffected in traf2 ( -/- ) MEF
McGee et al., Clin Exp Pharmacol Physiol 2006 : 3. These studies find possible roles for histone deacetylase 5 (HDAC5), adenosine monophosphate activated protein kinase ( AMPK ), peroxisome proliferator activated receptor gamma coactivator 1alpha ( PGC-1alpha ) and p38 mitogen activated protein kinase ( MAPK ) in regulating MEF2 through a series of complex interactions potentially involving MEF2 repression, coactivation and phosphorylation
Yin et al., Frontiers in physiology 2012 : Following the first demonstration that mitogen activated protein kinase p38 ( p38 MAPK ) directly phosphorylates and activates MEF2 to promote neuronal survival, several other kinase regulators of MEF2s have been identified