Nozu et al., Am J Physiol 1999
:
CCK ( 10 pM-10 nM ) and carbachol ( 0.1-100 microM ) dose dependently increased the amount of immunodetectable RhoA with a peak increase occurring at 3 min. High-affinity CCK-A-receptor agonists JMV-180 and CCK-OPE ( 1-1,000 nM ) did not increase the intensities of the RhoA band, suggesting that stimulation of RhoA is mediated by the low-affinity CCK-A receptor Le Page et al., Am J Physiol Cell Physiol 2003
:
CCK-A receptor activates RhoA through G alpha 12/13 in NIH3T3 cells