Deng et al., Am J Physiol Gastrointest Liver Physiol 2003
:
LPA prevented translocation of Bax from cytosol to mitochondria and increased the expression of the antiapoptotic Bcl-2 mRNA and protein
Goetzl et al., J Immunol 1999
:
At 10-9 M to 10-7 M, LPA and S1P significantly suppressed cellular levels of the apoptosis promoting protein Bax , without altering the levels of Bcl-xL or Bcl-2 assessed by Western blots and immunoassays