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RBBP5 — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lee et al., Proc Natl Acad Sci U S A 2009
(Cell Transformation, Neoplastic...) :
Consistent with the in vivo observations, and the demonstration of a direct interaction between p53 and ASCOM, cell based assays have revealed that
ASCOM , through ASC-2 and MLL3/4, acts as a p53 coactivator and is
required for H3K4-trimethyation and expression of endogenous
p53-target genes in response to the DNA damaging agent doxorubicin
Li et al., Mol Cell 2009
:
We further demonstrate that
MOF-MSL1v1 is specifically
required for optimal transcription activation of
p53 target genes both in vitro and in vivo