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TP53 — YBX1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: YBX1 — TP53 (direct interaction, pull down) Kojic et al., J Mol Biol 2004*
• IRef Biogrid Interaction: YBX1 — TP53 (direct interaction, pull down) Okamoto et al., Oncogene 2000*
• IRef Biogrid Interaction: YBX1 — TP53 (physical association, affinity chromatography technology) Okamoto et al., Oncogene 2000*
• IRef Biogrid Interaction: YBX1 — TP53 (physical association, affinity chromatography technology) Tian et al., J Cell Physiol 2011*
• IRef Hprd Interaction: YBX1 — TP53 (in vitro) Okamoto et al., Oncogene 2000*, Mertens et al., J Biol Chem 2002*
• IRef Hprd Interaction: YBX1 — TP53 (in vivo) Okamoto et al., Oncogene 2000*, Mertens et al., J Biol Chem 2002*
• IRef Intact Interaction: Complex of 88 proteins (association, tandem affinity purification) Agrawal et al., Cell cycle (Georgetown, Tex.) 2010
• IRef Ophid Interaction: YBX1 — TP53 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Okamoto et al., Oncogene 2000 : Gel mobility shift assays showed that the interaction of YB-1 with p53 stimulated the sequence-specific DNA binding of p53 to its consensus sequence
Zhang et al., Oncogene 2003 (Cell Transformation, Viral) : Nuclear localization of Y-box factor YB1 requires wild-type p53 ... In this paper, we explore a role for p53 in the nuclear localization of YB1
Lasham et al., J Biol Chem 2003 : Using reporter assays we show that YB1 represses transcription of the p53 promoter in a sequence-specific manner ... We also show that YB1 reduces endogenous levels of p53 , which in turn reduces p53 activity
Homer et al., Oncogene 2005 : We report that transcriptionally active p53 is required for nuclear localization of YB1
Zhang et al., Yi Chuan 2006 (Neoplasms) : It has been demonstrated that YB-1 represses transcription of the p53 promoter in a sequence-specific manner using specifically reporter assays
Sinnberg et al., Exp Dermatol 2012 (MAP Kinase Signaling System...) : We show that the PI3K/AKT and p53 signalling, growth factors and chemotherapeutic agents increase YB-1 promoter activity