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IL10 — SYK

Text-mined interactions from Literome

Slack et al., Eur J Immunol 2007 : Syk dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan
Gow et al., J Infect Dis 2007 (Candidiasis...) : Dectin-1 induced cytokine production through the following 2 pathways : Syk dependent production of the T-helper ( Th ) 2-type anti-inflammatory cytokine interleukin-10 and Toll-like receptor-Myd88 dependent stimulation of monocyte derived proinflammatory cytokines, such as tumor necrosis factor-alpha
Hatton et al., J Biol Chem 2011 (Epstein-Barr Virus Infections...) : Syk inhibition also reduces autocrine IL-10 production
Hatton et al., PloS one 2012 (Lymphoma, B-Cell) : Using small molecule inhibition and siRNA strategies in human B cell lines expressing a chimeric, signaling-inducible LMP1 protein, nerve growth factor receptor (NGFR)-LMP1, we show that NGFR-LMP1 utilizes Syk to activate PI3K/Akt signaling and induce IL-10 production