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IL12RB2 — IL17A

Text-mined interactions from Literome

Reddy et al., Cell Immunol 2007 : CNTO 1275 inhibited upregulation of CLA, IL-12R , IL-2Ralpha and CD40L expression and also inhibited IL-12- and IL-23 induced IFN-gamma, IL-17A , tumor necrosis factor (TNF)-alpha, IL-2, and IL-10 secretion
Toh et al., Cytokine 2009 : We report a novel negative regulatory role of IL-17 on IL-12R beta 2 expression associated with reduced IL-12 responsiveness
Toh et al., Ann Rheum Dis 2010 (Arthritis, Rheumatoid) : In RA, IL-12 hyporesponsiveness is associated with IL-17R mediated downregulation of IL-12Rbeta2 expression