Gene interactions and pathways from curated databases and text-mining

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CDK6 — UCN

Text-mined interactions from Literome

Usuda et al., Int J Cancer 2000 (Lung Neoplasms) : UCN-01 did not inhibit the CDK4 and CDK6 activities in both cells
Hsueh et al., Clin Cancer Res 1998 (Stomach Neoplasms) : UCN-01 , a protein kinase C/cyclin dependent kinase inhibitor , suppressed thymidylate synthase ( TS ) protein expression in a dose dependent manner with near complete suppression at 1 microM after a 24-h exposure in human gastric cancer cell line SK-GT5