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FCER2 — IFNG

Text-mined interactions from Literome

Hunot et al., J Neurosci 1999 (Parkinson Disease) : We show that, in vitro, interferon-gamma (IFN-gamma) together with interleukin-1beta (Il-1beta) and tumor necrosis factor-alpha (TNF-alpha) can induce the expression of CD23 in glial cells
Vella et al., Inflammation 1999 (Arthritis, Rheumatoid) : Moreover, we found that in our experimental conditions the presence of IFN-g or GM-CSF alone or in combination with IL-4 inhibited CD23 expression during the 24 h incubation
Kneitz et al., Leuk Res 2000 (Leukemia, Lymphocytic, Chronic, B-Cell) : It might be involved in the strong induction of CD23 on B-CLL cells after cotreatment with IL-4 and IFN-gamma, while in non-malignant B lymphocytes IFN-gamma leads to a reduction of IL-4 mediated CD23 expression
Harkins et al., Ann Allergy Asthma Immunol 2003 (Asthma...) : Regulation of CD23 in the chronic inflammatory response in asthma : a role for interferon-gamma and heat shock protein 70 in the TH2 environment
Yano et al., Nephron 1992 (Glomerulonephritis, IGA...) : We also examined the induction of surface CD23 expression on peripheral lymphocytes by interleukin (IL)-2, IL-3, IL-4, IL-5, IL-6, interferon (IFN)-gamma , IFN-alpha, phytohemagglutinin, concanavalin A, pokeweed mitogen, lipopolysaccharide and phorbol myristate acetate
Sukumar et al., J Immunol 2006 : In addition, IFN-gamma substantially enhanced CD23a and CD23b mRNA levels in CD40 stimulated FDCs. Curiously, IL-4 could also up-regulate FDC-CD23a but not -CD23b ... Anti-IFN-gamma dramatically inhibited FDC-CD23 in mice immunized with CFA, whereas anti-IL-4 had only a modest inhibitory effect ... In contrast with FDCs, IFN-gamma inhibited surface expression of murine B cell-CD23 as well as mRNA for B cell CD23a and -CD23b, whereas IL-4 dramatically enhanced message for both isoforms as well as protein expression
Watanabe et al., Immunol Lett 1990 (Leukemia, Eosinophilic, Acute) : Fc epsilon R2/CD23 expression was enhanced by both IFN-alpha and IFN-gamma , and suppressed by TGF-beta and dexamethasone
Peleman et al., Cell Immunol 1990 : The potentiation or the suppression of IgE synthesis by IFN-gamma is not explained by a differential effect of IFN-gamma on the production of soluble CD23 ( sCD23 ) ; indeed in both cases IFN-gamma slightly increases the IL4 induced production of sCD23
Delespesse et al., J Immunol 1989 : IFN-gamma increases IgE-BF synthesis by unfractionated PBMC, T cell depleted PBMC, adherent cells, and U937 cells suggesting that it induces monocytes to release IgE-BF, IFN-gamma suppresses the IL-4 induced Fc epsilon R II expression and IgE-BF production by highly purified B cells but not by PBMC or their T cell depleted fractions
Mayumi et al., Mol Immunol 1989 : PMA and IFN-gamma increased both surface Fc epsilon R2/CD23 expression and the Fc epsilon R2/CD23 mRNA levels
Defrance et al., J Exp Med 1987 : IFN-gamma strongly inhibited the induction of Fc epsilon RL/CD23 by IL-4
Rousset et al., J Immunol 1988 (Burkitt Lymphoma) : IFN-gamma also blocked IL-4 induced CD23 mRNA transcription in BL2 completely, whereas PGE2 ( 10 ( -7 ) M ) was partially inhibitory
Defrance et al., J Immunol 1987 : In striking contrast to the demonstrated antagonistic effect of interferon-gamma on the IL-4 induced expression of the low affinity receptor for IgE ( Fc epsilon RL/CD23 ), on B cells, it was found that interferon-gamma enhanced the IL-4 induced proliferation of anti-IgM preactivated B cells
Boltz-Nitulescu et al., J Leukoc Biol 1995 : Fc epsilon RII was also triggered by IFN-gamma , TNF-alpha, and IL-6 on all the cell lines, an effect blocked by calcitriol
Lee et al., Mol Immunol 1993 : It has been reported that the interleukin 4 (IL-4) specific induction of cell surface CD23 ( Fc epsilon RII ) is down-regulated by interferon-gamma (IFN-gamma) in monocytes and B cells ... Through nuclear run-on transcription and mRNA stability studies, we further demonstrate that the IL-4 induced CD23 gene expression is down-regulated by IFN-gamma mainly at post-transcriptional levels by decreasing mRNA stability
Halpern et al., Int Arch Allergy Immunol 1993 (Dermatitis, Atopic) : Interleukin-4 (IL-4), interferon-gamma (IFN-gamma) , and interferon-alpha ( IFN-alpha ) are involved in coordinate regulation of CD23 ... IFN-gamma also stimulates production of CD23 , but suppresses production of IgE and inhibits IL-4 mediated production of CD23 ... IFN-alpha also suppresses these IL-4 mediated activities and, in addition, suppresses IFN-gamma mediated stimulation of CD23 production ... Expression of CD23 by Langerhans cells is stimulated by IL-4 and IFN-gamma ... Coordinate regulation of CD23 by IFN-gamma and IL-4 may also be important in other allergic conditions, parasitic infections, and a variety of disease states
Armant et al., Eur J Immunol 1996 : We previously reported that soluble ( s ) CD23 potentiated the interleukin (IL)-2 induced interferon (IFN)-gamma production by T cells co-cultured with autologous monocytes in the absence of T cell receptor ( TCR ) engagement
Fu et al., Zhonghua Nei Ke Za Zhi 1996 (Asthma) : We investigated the regulation of CD23 expression by IL-4 and IFN-gamma in vitro, the results demonstrated that IFN-gamma could inhibit spontaneous and IL-4 induced expression of CD23
Dickensheets et al., J Immunol 1997 : IFN-gamma has been shown to inhibit induction of CD23 and 15-lipoxygenase in monocytes ; however, the effects of IFN-gamma on type I and type II IL-1R gene expression have not been defined
Corominas et al., Clin Exp Immunol 1998 (Asthma) : These results show that the modulation of CD23 expression is different on B and T cells, and that IFN-gamma acts differently in atopic and non-atopic individuals
Park et al., Mol Immunol 1998 : Although IFN-gamma alone did not induce CD23 mRNA transcription, Northern blot analysis revealed a transient up-regulation of the IL-4 induced CD23 mRNA by IFN-gamma within 2 h of IFN-gamma treatment in these tonsillar cells