◀ Back to MYB

MYB — RAG2

Pathways - manually collected, often from reviews:

• NCI Pathway Database C-MYB transcription factor network: Myb (MYB) → RAG2 (RAG2) (transcription, activates) Wang et al., Mol Cell Biol 2000*
  Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Kishi et al., Blood 2002 : Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells ... Furthermore, the dominant negative c-Myb mutant suppressed the activation of the RAG-2 promoter in a pre-B-cell line as well as in 293T cells
Jin et al., J Immunol 2002 : Cotransfection assays using a human embryonic kidney cell line ( 293T ) showed that LEF-1, c-Myb , and Pax-5 cooperatively activated the RAG-2 promoter, via their synergistic DNA binding