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LBP — RELA
Text-mined interactions from Literome
Hamann et al., Infect Immun 2005
(Acute-Phase Reaction) :
Here, we report that human high-dose
LBP ( hd-LBP ) suppresses binding of both R-type and S-type LPS to CD14 and
inhibits LPS induced nuclear translocation of
NF-kappaB , although cellular uptake of R-type LPS was found to be increased by hd-LBP
Fukuda et al., Invest Ophthalmol Vis Sci 2005
:
Combined stimulation with LPS and either sCD14 or
LBP also
induced the phosphorylation and degradation of IkappaB-alpha and the translocation of
NF-kappaB from the cytoplasm to the nucleus of corneal fibroblasts
Liu et al., Acta Pharmacol Sin 2006
(Drug-Induced Liver Injury) :
Upregulation of TNF-alpha and IL-6 mRNA might be related to increases in
LBP and CD14 mRNA expression and
activation of
NF-kappaB
Regueiro et al., Eur Respir J 2009
:
LBP and sCD14
inhibited the nontypeable Haemophilus influenzae ( NTHi ) -dependent secretion of IL-8 and the activation of
NF-kappaB and p38 mitogen activated protein kinase signalling pathways but they increased the internalisation of NTHi by airway epithelial cells