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GDI1 — RHO

Text-mined interactions from Literome

Kettritz et al., J Leukoc Biol 2000 : TNF-alpha mediated neutrophil apoptosis involves Ly-GDI , a Rho GTPase regulator
Genth et al., J Biol Chem 2003 : The increased stability of the GDI complex prevented binding of Rho to membrane associated players of the GTPase cycle such as the activating guanine nucleotide exchange factors and effector proteins
Zhang et al., Cancer Res 2006 (Breast Neoplasms...) : D4-GDI , a Rho GTPase regulator , promotes breast cancer cell invasiveness
Takaishi et al., Oncogene 1995 : Translocation of myc-RhoA to the membrane ruffling area was inhibited by prior microinjection into the cells of Rho GDI , a negative regulator of Rho which inhibits activation of Rho, or of C3, an exoenzyme of Clostridium botulinum which ADP-ribosylates Rho and inhibits its functions, indicating that both activation and functioning of Rho are essential for the translocation of Rho
Danley et al., J Immunol 1996 : Defective Rho GTPase regulation by IL-1 beta converting enzyme mediated cleavage of D4 GDP dissociation inhibitor ... We describe in this work specific proteolytic cleavage of D4 GDI , a critical regulator of Rho GTPase activity in inflammatory leukocytes, by IL-1 beta converting enzyme (ICE)
Takahashi et al., J Biol Chem 1997 : Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein