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GDI2 — RHO
Text-mined interactions from Literome
Kettritz et al., J Leukoc Biol 2000
:
TNF-alpha mediated neutrophil apoptosis involves
Ly-GDI , a
Rho GTPase
regulator
Genth et al., J Biol Chem 2003
:
The increased stability of the
GDI complex
prevented binding of
Rho to membrane associated players of the GTPase cycle such as the activating guanine nucleotide exchange factors and effector proteins
Zhang et al., Cancer Res 2006
(Breast Neoplasms...) :
D4-GDI , a
Rho GTPase
regulator , promotes breast cancer cell invasiveness
Takaishi et al., Oncogene 1995
:
Translocation of myc-RhoA to the membrane ruffling area was inhibited by prior microinjection into the cells of Rho
GDI , a negative
regulator of
Rho which inhibits activation of Rho, or of C3, an exoenzyme of Clostridium botulinum which ADP-ribosylates Rho and inhibits its functions, indicating that both activation and functioning of Rho are essential for the translocation of Rho
Danley et al., J Immunol 1996
:
Defective
Rho GTPase
regulation by IL-1 beta converting enzyme mediated cleavage of D4
GDP dissociation inhibitor ... We describe in this work specific proteolytic cleavage of D4
GDI , a critical
regulator of
Rho GTPase activity in inflammatory leukocytes, by IL-1 beta converting enzyme (ICE)
Takahashi et al., J Biol Chem 1997
:
Direct interaction of the Rho
GDP dissociation inhibitor with ezrin/radixin/moesin
initiates the activation of the
Rho small G protein