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INS — MLXIPL

Text-mined interactions from Literome

Sirek et al., Endocrinology 2009 : Insulin stimulates the expression of carbohydrate response element binding protein ( ChREBP ) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1 ... Insulin ( 10 nM ) also stimulated endogenous ChREBP expression in HepG2 and primary hamster hepatocytes ... More importantly, we found that the stimulatory effect of insulin on ChREBP promoter activity was dependent on the presence of the POU binding site, and insulin treatment reduced Oct-1 expression levels
da Silva Xavier et al., Biochem Biophys Res Commun 2010 : Conversely, adenovirus mediated over-expression of ChREBP in mouse pancreatic islets results in decreases in Pdx-1, MafA, Ins1 , Ins2 and GcK mRNA levels
Dubuquoy et al., J Hepatol 2011 (Fatty Liver) : We show that in the mouse liver, adiponutrin/PNPLA3 gene expression is under the direct transcriptional control of ChREBP ( carbohydrate-response element binding protein ) and SREBP1c ( sterol regulatory element binding protein1c ) in response to glucose and insulin , respectively