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FOXO3 — MYOCD
Text-mined interactions from Literome
Tan et al., J Biol Chem 2008
(Hypertrophy) :
Foxo3a could negatively
regulate myocardin expression levels through up-regulating catalase and the consequent reduction of ROS levels
Yang et al., PloS one 2013
:
We show using siRNA knockdown and ChIP assays that
FoxO3a , a downstream target of PI3K/Akt signaling,
represses myocardin promoter activity, and that Spry1 increases, while Spry4 decreases myocardin mRNA levels