Gene interactions and pathways from curated databases and text-mining

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CLDN2 — IFNG

Text-mined interactions from Literome

Willemsen et al., Clin Exp Immunol 2005 : Since the claudin family of tight junction proteins is proposed to be involved in barrier maintenance we studied the effect of IFN-gamma on claudin expression in relation to epithelial barrier function
Watson et al., J Pathol 2007 (Psoriasis) : We examined further whether exposure of keratinocytes in vitro to pro-inflammatory cytokines mimicked the observed changes in claudin expression seen in chronic plaque psoriasis ; lipopolysaccharide, interferon-gamma and tumour necrosis factor-alpha had no effect on claudin protein expression or distribution
Wisner et al., J Surg Res 2008 (Inflammatory Bowel Diseases) : Opposing regulation of the tight junction protein claudin-2 by interferon-gamma and interleukin-4