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IRF6 — SP1

Pathways - manually collected, often from reviews:

• FastForward regulation: SP1 → IRF6 (transcriptional regulation, unknown)
  Evidence: DNABINDING

Text-mined interactions from Literome

Ma et al., J Biol Chem 2001 : Furthermore, SB203580 inhibited LPS induced activation of Sp1 , as well as the promoter activity in cells transfected with a plasmid containing the Sp1 consensus sequence ... These results suggest that p38 mitogen activated protein kinase regulates LPS induced activation of Sp1 , which in turn regulates transcription of the hIL-10 gene
Ikeda et al., J Leukoc Biol 2002 : Furthermore, IL-10 suppressed lipopolysaccharide (LPS) induced NF-kappaB binding but not Sp-1
Liu et al., J Immunol 2003 : Coimmunoprecipitation experiments in intact cells indicated that LPS stimulated interaction between Sp1 and C/EBPbeta and delta ... These results suggested that the interaction between Sp1 and C/EBPbeta and delta induced by LPS cooperatively activated expression of the IL-10 gene
Chambers et al., Clin Exp Immunol 2004 (HIV Infections) : HIV infection of THP-1 myeloid cells resulted in decreased LPS induced nuclear factor binding to the NF-kappaB, AP-1, and Sp1 sites of the IL-12 p40 promoter
Hirasawa et al., Biochem Biophys Res Commun 2006 : By conducting electrophoretic mobility shift assays, we found that one of the transcription factors binding to the DNA probe containing the GC box sequence of the mouse HDC gene promoter region was Sp1 , and that levels of Sp1-DNA probe complexes were increased by stimulation with LPS although the protein levels of Sp1 were not changed
Ye et al., Biochim Biophys Acta 2007 : The protease responsible for the LPS induced Sp1 degradation has not been identified ... We conclude that LPS causes Sp1 degradation by inducing a unique trypsin-like serine protease, LISPDE
Oh et al., Neurosci Lett 2008 (Anoxia) : Consistently, LPS increased Sp1 DNA binding and its transcriptional activity ... Taken together, these results suggest that LPS induces HIF-1alpha mRNA expression and activation via NADPH oxidase and Sp1 in BV2 microglia
Iglesias et al., PloS one 2012 (Inflammation) : We examined the effect of 2 hrs LPS stimulation on early gene expression and its relation to chromatin remodeling ( H3 acetylation ; H3Ac ) and promoter binding of Sp1 and RNA polymerase II phosphorylated at serine 5 ( S5P RNAPII ), which is a marker for transcriptional initiation