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CD14 — IL8

Text-mined interactions from Literome

Iwagaki et al., Infect Immun 2000 : The purpose of this study was to compare and contrast the endotoxin neutralizing activities of two synthetic antiendotoxin peptides ( SAEP-2 and SAEP-4 ), PMB, and an LPS core-specific monoclonal antibody ( MAb ), WN1 222-5, based on their abilities to inhibit CD14 mediated target cell uptake of fluorescein isothiocyanate ( FITC ) -conjugated LPS, detected by flow cytometry and confocal microscopy, and LPS induced production of the proinflammatory cytokines, interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha), as measured by bioassays
Nemoto et al., J Immunol 2000 : As a result of CD14 proteolysis, IL-8 production by HGF was suppressed when triggered by 10 ng/ml LPS, but not by IL-1alpha, indicating that HLE inhibited a CD14 dependent cell activation
Sugawara et al., Infect Immun 2001 : PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies
Mao et al., Scand J Immunol 2002 (Bacteroidaceae Infections...) : CD14 mediated induction of interleukin-8 and monocyte chemoattractant protein-1 by a heat-resistant constituent of Porphyromonas gingivalis in endothelial cells
Böcker et al., Int J Colorectal Dis 2003 : However, CD14 was not required for LPS mediated induction of IL-8 in HT-29/p cells since neutralizing anti-CD14 antibodies left IL-8 levels unchanged
Takayama et al., Infect Immun 2003 : Augmentation of Actinobacillus actinomycetemcomitans invasion of human oral epithelial cells and up-regulation of interleukin-8 production by saliva CD14 ... The internalization of A. actinomycetemcomitans Y4 into HSC-2 cells was inhibited by cytochalasin B, indicating that the process was actin dependent, and depletion of CD14 from parotid saliva inhibited the invasion and, as a consequence, inhibited production of IL-8 ... Furthermore, human recombinant CD14 augmented invasion and IL-8 production ... These results suggest that saliva CD14 promoted the invasion of oral epithelial cells by A. actinomycetemcomitans and consequently augmented the production of IL-8 , playing an important role in innate immunity in the oral cavity
Hirata et al., J Clin Endocrinol Metab 2005 : However, LPS stimulated IL-8 secretion from EECs in the presence of soluble CD14
Blais et al., Invest Ophthalmol Vis Sci 2005 : In a dose-dependant manner, tear CD14 and LBP mediated the secretion of interleukin (IL)-6 and IL-8 by corneal epithelia cells when challenged with LPS
Sohn et al., Vet Res 2007 : Our results demonstrate that release of CD14 from PMN suppresses secretion of IL-8 , and may be an important regulatory mechanism for controlling excessive migration of PMN into the bovine mammary gland
Thorgersen et al., Infect Immun 2009 (Inflammation) : Anti-CD14 significantly reduced the levels of the E. coli induced proinflammatory cytokines TNF-alpha and IL-1beta, but not IL-8 , in a dose dependent manner
Brekke et al., Adv Exp Med Biol 2013 (Escherichia coli Infections...) : Inhibiting complement and CD14 efficiently reduced the expression of the E. coli induced cytokines IL-1beta, IL-6, IL-8 , and platelet derived growth factor bb
Dentener et al., J Immunol 1993 : We conclude that CD14 is involved in LPS induced release of TNF-alpha, IL-6, and IL-8 by monocytes and alveolar macrophages and that this receptor appears to be able to recognize LPS directly in the absence of serum
Landmann et al., J Infect Dis 1996 (Hemoglobinuria, Paroxysmal...) : The LPS induced IL-8 response was blocked by anti-CD14 and correlated with the serum CD14 level in sepsis patients