Kraatz et al., J Surg Res 1999
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LPS pretreatment induced tolerance decreased LPS stimulated MAP, SAP , and p38 kinase activation
Bocheński et al., J Physiol Pharmacol 1999
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Pretreatment with a PAF receptor antagonist ; WEB 2170 ( 5 and 25 mg/kg ) inhibited both PAP and SAP responses to LPS ( 4 mg/kg/min ) while an inhibitor of thromboxane synthesis ; Camonagrel ( 10 and 20 mg/kg ) abolished PAP response without a major effect on SAP response to LPS
Suzuki et al., J Immunol 2003
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Our results demonstrate that IRAK-4 is critical for the LPS induced activations of APCs Ford McIntyre et al., Int Immunopharmacol 2011
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Interestingly, stimulation with LPS activated allogeneic APCs significantly augmented the proliferation of DN Tregs compared to naïve allogeneic APCs