Gene interactions and pathways from curated databases and text-mining

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EGFR — MAP3K7

Text-mined interactions from Literome

Nishimura et al., Mol Cell Biol 2009 : TAK1 mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal regulated kinase : NF-{kappa}B independent survival pathways in tumor necrosis factor alpha signaling ... We have recently reported that TAK1 regulates the transient phosphorylation and endocytosis of epidermal growth factor receptor (EGFR) in a tyrosine kinase activity independent manner
Waiwut et al., Mol Cell Biochem 2011 : We have recently reported that TAK1 regulates phosphorylation of EGFR at Ser-1046/7 through p38 MAPK, which cooperates with NF-?B in TNF-a induced apoptosis