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CA2 — GNB2L1

Text-mined interactions from Literome

Patterson et al., Proc Natl Acad Sci U S A 2004 (Calcium Signaling) : RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release ... We demonstrate that RACK1 physiologically binds inositol 1,4,5-trisphosphate receptors and regulates Ca2+ release by enhancing inositol 1,4,5-trisphosphate receptor binding affinity for inositol 1,4,5-trisphosphate ... Overexpression of RACK1 or depletion of RACK1 by interference RNA markedly augments or diminishes Ca2+ release, respectively, without affecting Ca2+ entry
Sklan et al., Prog Neurobiol 2006 : When bound to the IP3 receptor, RACK1 regulates intracellular Ca2+ levels, potentially contributing to processes such as learning, memory and synaptic plasticity