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BTK — EPHB2

Text-mined interactions from Literome

Wu et al., J Immunol 2001 (Severe Combined Immunodeficiency) : Although both CD72 and BCR induced Btk dependent ERK activation, CD72 mediated proliferation is more resistant to blocking of ERK activity than that of BCR, as shown by the proliferation response of B cells treated with PD98059 and dibutyryl cAMP, agents that inhibit ERK activity
Lindvall et al., Biochem Biophys Res Commun 2002 : In addition, we have investigated the involvement of PI 3-K in the MAPKs and ERK and JNK phosphorylation, in the presence or absence of Btk
Jiang et al., J Exp Med 1998 : BCR mediated activation of ERK2, although maintained in Lyn-deficient cells, was abolished in Syk-deficient cells and partially inhibited in Btk-deficient cells, indicating that BCR mediated ERK2 activation requires Syk and that sustained ERK2 activation requires Btk